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Usable news + tips Bonnie Schiedel Broken hearts Male and female hearts are not created equal. Researchers at the University of British Columbia (UBC)in Vancouver looked at 32,856 Canadians with chest pain who underwent cardiac catheterization to check for reduced blood flow to the heart. The gender differences were striking: 23% of women, compared with 7% of men, had normal-looking arteries, even though the women were more likely to be older and have high blood pressure, chronic obstructive pulmonary disease, peripheral vascular disease and a history of stroke. Women were also four times more likely to be readmitted to the hospital for recurring chest pain in the six months after catheterization. “Cardiac catheterization may not be the best way to diagnose coronary disease in women,” says study co-author Dr. Karin Humphries, an associate professor in the UBC medical school’s department of cardiology. “Physicians should consider additional diagnostic tests — such as stress echocardiography or nuclear perfusion — in women with chest pain, as well as treatment with beta blockers and ASA.” Move of the month Check Your Posture
Your medical IQ Epigenetics is...
Answer: 4 The Greek preposition epi (upon) refers to changes in how genes are expressed on top of, or in addition to, the traditional mode of expression through different DNA sequences. And these environment-related changes may be passed on to descendants. A Swedish study, for example, found that men whose diets had been restricted in childhood (due to crop failures) had children and grandchildren who were unlikely to die of cardiovascular disease. Having plenty of food during childhood, on the other hand, meant that men had descendants who were more likely to die of diabetes. Epigenetic influences on genes may play a role in cancer, diabetes, Crohn’s disease and schizophrenia. Myth or Reality? Your eyes are safe from ultraviolet rays under water.
Fast Fact 70% The proportion of patients who need stem-cell transplants (often for blood diseases such as leukemia and aplastic anemia) and don’t have a match within their own families. Want to help? If you’re healthy and between the ages of 17 and 50, contact Canadian Blood Services at www.onematch.ca or 1 888 2 DONATE to find out how to place your name in the database of potential donors. Eat this! A crisp wedge of watermelon is the perfect way to quench your thirst on a hot summer day — and get some valuable nutrients, too. “Watermelon is a good source of lycopene, an antioxidant pigment that shows promise in fighting cancer, especially prostate cancer, and is also associated with a reduced risk of heart disease, diabetes and macular degeneration,” says Karolina Sekulic, an Edmonton-based registered dietitian. “Two cups of diced watermelon are also packed with vitamins A and C and potassium — all for about 90 calories.” Tip Keep that uncut watermelon out of the fridge. A study in the Journal of Agriculture and Food Chemistry found that ripe watermelons stored at 21°C (70°F) contained as much as 40% more lycopene than those stored at 13°C (55°F). A Good Egg New research from Laval University in Quebec City may help more couples conceive through in vitro fertilization (IVF). Scientists took samples of the follicular cells that surround eggs harvested from the ovaries for IVF. “We compared the follicular cells from the women who did become pregnant with those who did not and identified eight genetic markers that were expressed more abundantly in the successful pregnancies,” says lead researcher Dr. Marc-André Sirard, co-director of Laval’s Centre of Research in Biology of Reproduction. “Currently, promising eggs are identified through visual inspection. Our analysis is another way to identify the eggs that have the best chance of success.” This technique may help fertility technicians choose only one high-quality embryo to transfer to a woman’s uterus, thereby decreasing the incidence of multiple births and the health risks, such as premature birth, that go along with them. Mole Poll From the pictures below, choose the one that shows a normal mole.
Answer Trick question — they all illustrate abnormal moles. The ABCs of abnormal moles A is for asymmetry. One side of the mole is different from the other. B is for border. The edges of the mole are irregular and not sharply defined. C is for colour. The colour of the mole varies and may include brown, red, black, grey or white. D is for diameter. The mole is larger than 1⁄2 inch (12.7 mm). E is for evolution. There’s a change in the mole’s colour, size or shape, or in symptoms such as tenderness, itching or bleeding. If you have an unusual mole, don’t panic. “Some people have dozens of weird moles, yet we don’t remove them just because they’re there,” says Dr. Cheryl Rosen, a Toronto dermatologist and national director of the Canadian Dermatology Association’s National Sun Awareness Program. “However, ask your doctor to examine it, especially if the mole appears to be changing. An abnormal mole can go on to become a melanoma, a potentially lethal skin cancer. Fortunately, most don’t. “An unusual mole is, however, a hint to be even more careful about sun exposure.” (A melanoma can also develop in previously normal skin, where there was no mole.) So, this summer, wear protective clothing in the sun and use a broad-spectrum sunscreen that guards against both UVA and UVB rays. You ask, we answer Skeeter Scare What is West Nile virus, and how do I protect myself? West Nile virus is an infectious disease originating in Africa and transmitted by certain types of mosquitoes in Canada. It may cause no symptoms at all or induce a fever and flu-like symptoms, sometimes with a rash or swollen lymph glands. Its long-term effects are not known. According to the Public Health Agency of Canada, there were 2,353 reported cases in 2007. For most people, the disease is self-limiting and they recover on their own. “The risk is when the disease invades the central nervous system and results in meningitis or encephalitis,” says Dr. Robbin Lindsay, a research scientist at the National Microbiology Laboratory in Winnipeg. That can lead to hospitalization — even death. Those with chronic diseases and weakened immune systems are at the greatest risk for complications. So what’s the best way to protect yourself? “Avoid mosquitoes,” says Lindsay. “Mosquitoes bite — that’s how they earn their living. They’re going to find the unprotected areas on you and bite.” For outdoor activities from dusk to dawn, skeeters’ prime biting time, wear loose light-coloured clothing, a hat, long sleeves, long pants and closed shoes with socks. Use mosquito netting on strollers. Apply DEET-based insect repellents but follow product safety instructions, especially for children. Do not use on infants under six months of age or on broken skin. Make sure all windows ae tightly screened. And empty standing water from places where it collects: wheelbarrows, buckets, flowerpots and eavestroughs. For more details, go to www.westnilevirus.gc.ca. Too much of a good thing? I’m trying to up my fibre intake, but what happens if I consume too much? Although getting too much fibre is not a widespread problem in Canada, excess intake can interfere with the proper absorption of vitamins, minerals, protein and calories in the digestive tract. It can also affect the absorption of some medications. “The common problem with fibre isn’t usually taking more than the Consuming large amounts of non-dietary sources of fibre, such as supplements for bowel regularity, can result in excessive intake. The recommended daily amount of fibre for women ages 19 to 50 is 25 grams; for men it’s 38 grams. After age 50, women need 21 grams and men 30. Most Canadians consume less than 11 grams a day. Cramping her style My 10-year-old daughter’s leg cramps interfere with her summer activities. What causes these cramps?
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